Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM21025 ((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against the Opioid receptor delta 1 | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001551 (22-cyclopropylmethyl-9-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DSLET binding to Opioid receptor delta 2 at 4 nM concentration | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001554 (22-cyclopropylmethyl-6-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DSLET binding to Opioid receptor delta 2 at 4 nM concentration | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001553 (22-cyclopropylmethyl-8-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DPDPE binding to Opioid receptor delta 1 at 4 nM concentration expressed as dissociation constant | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001552 (22-cyclopropylmethyl-7-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DPDPE binding to Opioid receptor delta 1 at 4 nM concentration expressed as dissociation constant | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021328 (3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against the Opioid receptor delta 1 | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001554 (22-cyclopropylmethyl-6-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DSLET binding to Opioid receptor delta 2 at 4 nM concentration | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001551 (22-cyclopropylmethyl-9-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DPDPE binding to Opioid receptor delta 1 at 4 nM concentration expressed as dissociation constant | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against the Opioid receptor delta 1 | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001552 (22-cyclopropylmethyl-7-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DPDPE binding to Opioid receptor delta 1 at 0.25 nM concentration expressed as dissociation consta... | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001553 (22-cyclopropylmethyl-8-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DSLET binding to Opioid receptor delta 2 at 0.25 nM concentration | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119128 (GS7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001551 (22-cyclopropylmethyl-9-isothiocyanato-14-oxa-11,22...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Compound was evaluated for its effect towards [3H]-DSLET binding to Opioid receptor delta 2 at 4 nM concentration | J Med Chem 35: 4086-91 (1992) BindingDB Entry DOI: 10.7270/Q27S7MQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50452273 (Dihydromorphine) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against the Opioid receptor delta 1 | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119129 (GS8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 160 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019091 (3-(3-Hydroxy-phenyl)-2-methyl-1-phenethyl-piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019093 (1-Cyclopropylmethyl-3-(3-hydroxy-phenyl)-piperidin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50576969 (CHEMBL4863362) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP3A4 assessed as dissociation constant | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113496 BindingDB Entry DOI: 10.7270/Q2S1869N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119126 (GS5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 400 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176903 (CHEMBL3814877) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 588 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 588 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019097 (1-Cyclopropylmethyl-3-(3-hydroxy-phenyl)-2-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019094 (1-Allyl-3-(3-hydroxy-phenyl)-piperidine-3-carboxyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 715 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019095 (1-Allyl-3-(3-hydroxy-phenyl)-2-methyl-piperidine-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176904 (CHEMBL3814479) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM8610 (1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Binding affinity to His-tagged CYP3A4 (unknown origin) expressed in Escherichia coli DH5alpha assessed as type 2 spectral shift by measuring dissocia... | J Med Chem 63: 1415-1433 (2020) Article DOI: 10.1021/acs.jmedchem.9b02067 BindingDB Entry DOI: 10.7270/Q2NS0Z6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019098 (3-(3-Hydroxy-phenyl)-1,2-dimethyl-piperidine-3-car...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50576968 (CHEMBL4871524) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP3A4 assessed as dissociation constant | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113496 BindingDB Entry DOI: 10.7270/Q2S1869N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119125 (GS4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50576966 (CHEMBL4864434) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP3A4 assessed as dissociation constant | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113496 BindingDB Entry DOI: 10.7270/Q2S1869N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119127 (GS6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019092 (3-(3-Hydroxy-phenyl)-1-methyl-piperidine-3-carboxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC... | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50576967 (CHEMBL4862783) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP3A4 assessed as dissociation constant | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113496 BindingDB Entry DOI: 10.7270/Q2S1869N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50576970 (CHEMBL4863066) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP3A4 assessed as dissociation constant | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113496 BindingDB Entry DOI: 10.7270/Q2S1869N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119126 (GS5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176905 (CHEMBL3814345) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176907 (CHEMBL3814729) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM119125 (GS4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.31E+4 | n/a | n/a | n/a | 7.4 | n/a |
University of California at Irvine | Assay Description Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots... | Biochemistry 52: 4474-81 (2013) Article DOI: 10.1021/bi4005396 BindingDB Entry DOI: 10.7270/Q2PZ57GJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176908 (CHEMBL3814075) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50417104 (CHEMBL1256004) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.50E+6 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176909 (CHEBI:16227 | Pyridine) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.50E+6 | n/a | n/a | n/a | n/a | n/a |
University of California-Irvine Curated by ChEMBL | Assay Description Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio... | J Med Chem 59: 4210-20 (2016) Article DOI: 10.1021/acs.jmedchem.5b01146 BindingDB Entry DOI: 10.7270/Q2Q52RKB | |||||||||||
More data for this Ligand-Target Pair |